CD36 Gene Polymorphism and Susceptibility to Nephropathies

CD36 Gene Polymorphism and Susceptibility to Nephropathies

Introduction: Renal diseases affect huge populations in Morocco and abroad. Genetic polymorphisms (SNPs) in scavenger receptors such as CD36 have been implicated in the pathogenesis of diabetes, hypertension, atherosclerosis and cardiovascular diseases. Since CD36 gene expression contributes to these leading causes of kidney disease, we proposed to study the association of two of its polymorphi...

MTHFR rs1801133 Gene Polymorphism and Autism Susceptibility

Background: It is believed that environmental and genetic factors may be responsible for autism. Methylenetetrahydrofolate reductase (MTHFR) and its gene polymorphisms have been shown to be implicated as risk factors in autism. Objectives: To analyze MTHFR C677T polymorphism (rs1801133) in autistic patients. Materials and Methods: This study was carried out in 2014 and 2015 in northern Ir...

Is human dectin-1 Y238X gene polymorphism related to susceptibility to recurrent vulvovaginal candidiasis?

Background and Purpose: Vulvovaginal candidiasis is a frequent disease affecting approximately more than %75 of all childbearing women at least once in their lifetime by overgrowth of opportunistic Candida species. Recurrent vulvovaginal candidiasis (RVVC) is common in otherwise healthy individuals. Several risk factors were reported to contribute to RVVC susceptibility. A polymorphism in Decti...

Studying the Association between STAT4 Gene Polymorphism and Susceptibility to Rheumatoid Arthritis Disease: An Updated Meta-Analysis

Association between Lymphotoxin (LT-A) Gene Polymorphism and Susceptibility to Chronic Hepatitis C Infection in Iranian Patients

Background & Aims: Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease worldwide. The clearance of the HCV is dependent on cytokines control led by genetic. The purpose of this study was to investigate the impact of Lymphotoxin (LT-A) polymorphism at +252 in susceptibility to chronic hepatitis C. Methods: In this case-control study, 120 individuals infected by HCV and ...